Is There a Link between Nickel Allergy and Coronary Stent Restenosis?

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Is there a link between nickel allergy and coronary stent restenosis?

Although many patients with coronary artery disease are being treated by coronary stents, in-stent restenosis is the major limitation of percutaneous coronary stenting procedures. Most stents are made of stainless steel, and that, allergic reactions to nickel ions released from coronary stainless-steel stents may be one of the triggering mechanisms for in-stent restenosis. We aimed to evaluate ...

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Does nickel allergy play a role in the development of in-stent restenosis?

OBJECTIVES It was suggested that coronary in-stent restenosis might be triggered by allergy to nickel and molybdenum ions released from stainless-steel stents. We sought to explore any possible relationship between nickel allergy and in-stent restenosis. MATERIALS AND METHODS 50 patients were studied, who underwent elective follow-up coronary angiography for recurrent symptoms after prior cor...

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lipoprotein(a), an ldl variant, has been claimed to have a role in atherogenesis and therefore coronary artery disease (cad). however, its production and atherogenecity seems to vary among ethnic groups. in order to study the possible correlation between levels of lp(a) and cad in iranian patients who suffered myocardial infarction (mi), a case-control study was carried out on 120 mi patients a...

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Relation of Nickel Allergy with in-Stent Restenosis in Patients Treated with Cobalt Chromium Stents

BACKGROUND In-stent restenosis (ISR) is the major limitation of percutaneous coronary stenting procedure. The elements like nickel, chromate and molybdenum are known to cause contact allergy. Hypersensitivity reaction, against these metal ions, may be one of the reasons of ISR. Cobalt chromium coronary stents, which are increasingly being used in percutaneous coronary interventions, have more n...

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ژورنال

عنوان ژورنال: The Tohoku Journal of Experimental Medicine

سال: 2005

ISSN: 0040-8727,1349-3329

DOI: 10.1620/tjem.206.243